Human Pegivirus (GB Virus Type C) and Its Relationship with HIV

GB Virus type C and its relationship with Human Immunodeficiency Virus

Despite of the relative success of Highly Active Anti Retroviral Therapy (HAART), HIV/AIDS pandemic still remains as one of the major threats to world health. Due to the limitations of the current treatments and the lack of success in the development of a preventive vaccine, the discovery of novel mechanisms involved in HIV replication has become of paramount importance. GB Virus type C or Hepa...

Deep sequencing identifies two genotypes and high viral genetic diversity of human pegivirus (GB virus C) in rural Ugandan patients.

Human pegivirus (HPgV), formerly 'GB virus C' or 'hepatitis G virus', is a member of the genus Flavivirus (Flaviviridae) that has garnered significant attention due to its inhibition of HIV, including slowing disease progression and prolonging survival in HIV-infected patients. Currently, there are six proposed HPgV genotypes that have roughly distinct geographical distributions. Genotypes 2 an...

GB virus type C: a beneficial infection?

the past hospitalization and its association with suicide attempts and ideation in patients with mdd and comparison with bmd (depressed type) group

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GB virus C: cellular interactions, HIV inhibition and natural history

GB virus C (GBV-C) is a nonpathogenic lymphotropic virus that replicates in B and T lymphocytes. Infection with GBV-C is documented worldwide and is common: between 1% and 5% of healthy blood donors are viremic at the time of donation. Antibodies to GBV-C proteins are not usually detected during viremia, and antibodies to the GBV-C envelope glycoprotein E2 develop following the clearance of vir...